Abstract

ABSTRAK


 


Penyakit jantung koroner adalah suatu keadaan yang diakibatkan oleh adanya penyempitan dan penyumbatan pembuluh darah yang mengalirkan darah ke otot jantung, sehingga otot jantung akan kekurangan darah dan tidak mendapatkan oksigen untuk pekerjaannya. Penelitian ini merupakan penelitian deskriptif pengambilan data secara retrospektif dengan mengambil data dari rekam medis dengan diagnosa Penyakit Jantung Koroner di Instalasi Rawat Inap RSUD Sayidiman Magetan periode 2022. Diperoleh jumlah sampel yang memenuhi kriteria inklusi yaitu sebanyak 91 pasien.


Hasil penelitian ini menunjukan bahwa pasien yang mengalami penyakit jantung korone mendapatkan terapi antihipertensi tunggal golongan ACE Inhibitor berupa Captopril dan Ramipril sebanyak 27,5% , golongan Beta Blocker berupa bisoprolol 16,5%, golongan angiotensin reseptor blocker berupa candesartan sebanyak 8,8%. Pada terapi antihipertensi kombinasi golongan ACE Inhibitor+ Beta Blocer berupa bisoprolol + ramipril, captopril sebanyak 35,2%, golongan angiotensin reseptor blocker + Beta Blocker sebanyak 12,1%. Hasil analisis hubungan penggunaan antihipertensi tunggal dan kombinasi terhadap efektivitas terapi menggunakan metode paired sampe test diperoleh p-value 0,000 pada tekanan darah sistolok dan diastolik. Maka p value 0,000 <0,05 yang artinya ada hubungan efektivitas penggunaan antihipertensi tunggal dan kombinasi dengan penurunan tekanan darah sistolik dan diastolik.


 


Kata kunci:  : Efektivitas, Hipertensi, Penyakit Jantung Koroner


 


ABSTRACT


 


Coronary heart disease is a condition caused by the blockage of blood vessels that drain blood to the heart muscle so it will lack of blood flow and oxygen for it to work. This study aims to determine the type of antihypertensive used in coronary heart patients and its effectiveness in reducing blood pressure in coronary heart patients hospitalized at Dr. Sayidiman Magetan for the 2022 period. This research is a retrospective descriptive study of data collection by taking data from medical records with a diagnosis of Coronary Heart Disease at the Inpatient Installation of Sayidiman Magetan Hospital for the 2022 period. The number of samples that met the inclusion criteria was obtained, namely 91 patients.


The results of this study showed that patients with coronary heart disease received 27.5% single antihypertensive therapy for the ACE Inhibitor group, Captopril, and Ramipril, 16.5% for the Beta Blocker group, 8.8% for the angiotensin receptor blocker, candesartan group. In combination with antihypertensive therapy, the ACE Inhibitor + Beta Blocker group consisted of bisoprolol + ramipril, 35.2% of captopril, and 12.1% of the angiotensin receptor blocker + Beta Blocker. The results of the analysis of the relationship between the use of single and combination antihypertensive agents on the effectiveness of therapy using the paired sample test method obtained a p-value of 0.000 in systolic and diastolic blood pressure. Then the p-value is 0.000 <0.05, which means that there is a relationship between the effectiveness of using single and combined antihypertensives with a decrease in systolic and diastolic blood pressure.


 


Key words: Effective, Hypertension, Coronary Heart Disease.